Skin Cancer Arising in Scars: A Systematic Review

BACKGROUND
Despite numerous case reports, epidemiologic evidence regarding true rate of skin cancer in scars of any etiology is sparse.


METHODS
Systematic literature review of all published epidemiologic studies on skin cancer in scar tissue from surgery, ulcers, or burns using citation databases and manual review.


RESULTS
There were no epidemiologic data to quantify risk of skin cancer in surgical scars or chronic ulcers. Two eligible cohort studies were identified, from Denmark and Sweden, in which skin cancers in 16, 903 and 37,095 burn patients, respectively, were ascertained through cancer registry follow-up. ...

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