Sunday, June 5, 2011

Low-dose UVA1 phototherapy for scleroderma: what benefit can we expect?

Abstract

Background  The first reports of the application of ultravioletA1 (UVA1) phototherapy for scleroderma go back only to 1995, but since then, several studies have proven its effectiveness in this disease.


Objectives  To evaluate the effectiveness of low-dose (35 J/cm2) UVA1 phototherapy in patients with scleroderma, trying to define the subgroups that benefit most from this treatment.


Methods  Retrospective analysis of patients diagnosed with clinical and/or histological scleroderma, undergoing low-dose UVA1 phototherapy between 2003 and 2010.


Results  We studied 21 patients (20 women and one man) aged 10–75 years (mean 50). Eighteen with morphea performed a ...

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