Background: Filaggrin is a key protein involved in maintaining skin barrier function and hydration. Mutations in the filaggrin gene (FLG) cause ichthyosis vulgaris (IV) and are a major predisposing factor for atopic dermatitis (AD) in individuals of European and Asian descent. It has been proposed that FLG mutations are population-specific and a difference in the spectra of mutations between different ancestral groups has been described. However, it is unknown whether FLG mutations in the African population are a causative genetic factor for IV and predispose to AD, or whether other ...
Novel filaggrin mutation but no other loss-of-function variants found in ethiopian atopic-dermatitis patients is a post from: Skincare
Novel filaggrin mutation but no other loss-of-function variants found in ethiopian atopic-dermatitis patients via BuzzBlazer.com
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