Background. Type I interferon (IFN) has been reported to have an important role in the development of cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE). A new subset of CD4+ T cells, T helper (Th)17 cells, also plays a role in the development of autoimmunity.
Aim. To investigate expression of interleukin (IL)-17 and IFN-α in different CLE subsets, and their associations with the pathogenesis of LE.
Methods. Skin tissue samples from 33 cases, including chronic discoid LE (n = 24), acute (A)CLE (n = 4), subacute CLE (n = 1) and lupus panniculitis (n = 4) were collected for ...
Expression of interleukin-17 is correlated with interferon-α expression in cutaneous lesions of lupus erythematosus is a post from: Skincare
Expression of interleukin-17 is correlated with interferon-α expression in cutaneous lesions of lupus erythematosus via BuzzBlazer.com
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