Sunday, June 19, 2011

Toxic epidermal necrolysis and Stevens-Johnson syndrome at the Prague Burn Centre 1998–2008

Abstract

Background  Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are skin disorders characterized by extensive necrosis of the mucous membranes and the epidermis caused by an autoimmune response.


Objectives  To present experience of treating TEN and SJS at the Prague Burn Centre (PBC) 1998–2008.


Methods  22 patients with the diagnosis TEN or SJS were enrolled. We collected data including the extent of the skin involvement, the ratio of men : women, the average age, the mortality rate, presence of comorbidities, the length of hospital stay, the period from the first symptoms to the admission ...

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