Differences between familial and sporadic cases of vitiligo

Abstract

Background  Most cases of vitiligo are sporadic, but about 10–36% of the patients have positive family history.


Objective  The aim of our study was to describe differences between familial and sporadic cases of vitiligo.


Methods  A total of 186 adult vitiligo patients were examined, in 173 of whom the level of thyroid peroxidase antibodies, gastric parietal cell antibodies (PCA), antinuclear antibodies (ANA), anti-adrenal cortex antibodies and rheumatoid factor in blood was measured. All patients were divided in two groups: the cases with positive family history of vitiligo (51) and the sporadic cases ...

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