A Systematic Review of worldwide incidence of Non-melanoma skin cancer

Abstract

Background:  Non-melanoma skin cancer (NMSC) is the most common cancer affecting Caucasians and the incidence is increasing worldwide. This systematic review brings together 75 studies conducted over the past half decade to look at geographic variations and trends worldwide in NMSC, and specifically incidence data is compared to recent UK cancer registry data.


Materials and Methods:  Following the development of a comprehensive search strategy, an assessment tool was adapted to look at the methodological quality of the eligible studies.


Results:  Most of the studies focused on Caucasian populations in Europe, USA and ...

A Systematic Review of worldwide incidence of Non-melanoma skin cancer is a post from: Skincare

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Role of GSTs in Melanoma Susceptibility: Association with rs1695 GSTP1 Polymorphism.

Summary

Background:  Glutathione S-transferases (GSTs) GSTM1, GSTT1 and GSTP1 are multifunctional enzymes involved in the detoxification of a wide range of reactive oxygen species produced during melanin synthesis and oxidative stress processes.


Objectives:  Single nucleotide polymorphisms (GSTP1) and copy number variants (GSTM1 and GSTT1) may be candidate low-penetrance variants with a role in susceptibility to malignant melanoma (MM).


Methods:  In this case-control study, 562 Spanish sporadic melanoma patients and 338 cancer-free control subjects were included, and the role of these GST polymorphisms was investigated. Genotypes were established by quantitative real time-PCR for GSTM1 ...

Role of GSTs in Melanoma Susceptibility: Association with rs1695 GSTP1 Polymorphism. is a post from: Skincare

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Primary cutaneous nocardiosis caused by Nocardia beijingensis

Primary cutaneous nocardiosis caused by Nocardia beijingensis is a post from: Skincare

Primary cutaneous nocardiosis caused by Nocardia beijingensis is a post from: Skincare

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Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp – a randomized multicentre study

Abstract

Background:  Photodynamic therapy (PDT) is an attractive therapy for non-melanoma skin cancers and actinic keratoses (AKs). Daylight-mediated PDT is a simple and tolerable treatment procedure for PDT. Methyl aminolevulinate (MAL) -PDT is approved for the treatment of thin or non-hyperkeratotic actinic keratoses on the face and scalp. However, thick AK lesions are often treated as well when present in the field-cancerized treatment area.


Objectives:  The aim of the study was in a randomized multicentre study to evaluate efficacy of daylight-mediated PDT for different severity grades of AKs.


Methods:  145 patients with a ...

Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp – a randomized multicentre study is a post from: Skincare

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A case of false negative monochromator phototesting in a patient with chronic actinic dermatitis taking Prednisolone

A case of false negative monochromator phototesting in a patient with chronic actinic dermatitis taking Prednisolone is a post from: Skincare

A case of false negative monochromator phototesting in a patient with chronic actinic dermatitis taking Prednisolone is a post from: Skincare

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Treatment of Anetoderma Occurring After Resolution of Stevens–Johnson Syndrome Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser

Treatment of Anetoderma Occurring After Resolution of Stevens–Johnson Syndrome Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser is a post from: Skincare

Treatment of Anetoderma Occurring After Resolution of Stevens–Johnson Syndrome Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser is a post from: Skincare

Treatment of Anetoderma Occurring After Resolution of Stevens–Johnson Syndrome Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser via BuzzBlazer.com

Double Trichophytic Closure with Wavy Two-Layered Closure for Optimal Hair Transplantation Scar

Double Trichophytic Closure with Wavy Two-Layered Closure for Optimal Hair Transplantation Scar is a post from: Skincare

Double Trichophytic Closure with Wavy Two-Layered Closure for Optimal Hair Transplantation Scar is a post from: Skincare

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