Sunday, June 5, 2011

The effect of topically applied corticosteroids on interleukin 1β levels in patients with atopic dermatitis

Abstract

Background  Atopic dermatitis (AD) is a chronic recurrent disease of childhood. The therapeutics of AD needs to be more tailored given the new cytokine antibodies available. In this scenario we considered interleukin 1 beta (IL-1β) levels before and after therapy with topical corticosteroids.


Objectives  To measure the IL-1β levels before and after treatment in patients with AD after 75% improvement in scoring for atopic dermatitis index.


Methods  Forty-five subjects with AD were treated with betamethasone ointment and their IL-1β level was measured prior to and following treatment.


Results  The IL-1β levels were raised ...

The effect of topically applied corticosteroids on interleukin 1β levels in patients with atopic dermatitis is a post from: Skincare




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