Tape stripping in conjunction with scanning Raman microscopy was used for assessing the lateral and vertical distribution of an organic particulate UV filter, methylene bis-benzotriazolyl tetramethylbutylphenol (MBBT), in a sunscreen formulation. On the volar forearms of three volunteers, 1 mg cm−2 formulation containing 10% MBBT was applied, and the average amount of MBBT was measured by Raman scanning microscopy in 15 consecutive tape strippings. The recovery of MBBT was 91.1% with 30.2% localizing on the skin surface (first strip), 42.5% in the upper stratum corneum (strips 2–5) and from 3.6 down to ...
Surface distribution and depths profiling of particulate organic UV absorbers by Raman imaging and tape stripping is a post from: Skincare
Surface distribution and depths profiling of particulate organic UV absorbers by Raman imaging and tape stripping via BuzzBlazer.com
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