Sunday, June 12, 2011

New horizons for cutaneous microbiology: the role of biofilms in dermatological disease

Abstract

Human skin is colonized by bacteria. The development of new genomic microbiological techniques has revealed that the bacterial ecology of human skin is far more complex than previously imagined, and includes many fastidious or non-cultivable bacterial species which are found on both normal and diseased skin.


In nature, the predominant bacterial phenotype on epithelial surfaces is that the organisms are organized within a biofilm. This contrasts with the widely held belief that bacteria are planktonic – i.e. free-floating single cells. Biofilms are sessile bacterial communities encased in an extracellular matrix that ...

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