Monday, January 9, 2012

Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis

Abstract

Background  Topical nitrogen mustard is a chemotherapeutic agent used in treatment of mycosis fungoides (MF).


Objective  To evaluate the response and side effects in patients with MF and parapsoriasis treated with topical nitrogen mustard.


Methods  A retrospective study of treatment response in 116 patients diagnosed with MF and 71 patients with parapsoriasis and treated with topical nitrogen mustard from 1991 to 2009.


Results  Overall response rate and complete response (CR) rate was 91.4% and 53.4% in patients with MF and 90.1% and 40.8% in patients with parapsoriasis, respectively. Relapse following CR was observed ...

Topical nitrogen mustard therapy in patients with mycosis fungoides or parapsoriasis is a post from: Skincare




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