Tuesday, January 3, 2012

Development and Application of a HPLC Method for Eight Sunscreen Agents in Suncare Products

Abstract

This work describes the development, validation and application of a simple and fast HPLC-DAD method for the determination of eight sunscreen agents: benzophenone-3, octocrylene, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate (used in two isomeric forms), butyl methoxydibenzoylmethane, 4-methylbenzylidene camphor and ethylhexyl dimethyl PABA in sunscreen formulations. The separation of the eight sunscreen compounds was achieved using an ACE C18 column (250 mm x 4.6 mm, 5 μm), with a column temperature 20 °C, and a mobile phase of 88:12 (v/v) methanol-water with isocratic elution. Column temperature strongly influences the retention time ...

Development and Application of a HPLC Method for Eight Sunscreen Agents in Suncare Products is a post from: Skincare




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