Aim
A comparison of permeation ability of selected semi-permanent hair dyes and an attempt to estimate the influence of fundamental physicochemical parameters on dyes’ epidermal penetration rate.
Methods
Dyes’ permeation ability through liposome membrane (as a model of stratum corneum) with side-by-side cells was assessed.
Results
It has been shown that the chosen dyes are capable of permeating the membrane. High penetration coefficients (Kp) were obtained for a simple nitrophenylenediamines and nitroaminophenols. Their N-, O-hydroxyalkyl substitution significantly limits penetration. H-bonding capability has a major impact on the investigated dyes’ permeation ability. Substituents with H-bonding properties ...
Liquid-crystalline membrane permeation ability for selected nitro hair dyes is a post from: Skincare
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