Background
Thinner and shorter needles for subcutaneous administration are continuously developed. Previous studies have shown that a thinner needle causes fewer occurrences of painful needle insertions and that a shorter needle decreases the occurrence of painful intramuscular injections. However, little is known about local drug delivery in relation to needle length and thickness. This study aimed to compare deposition depth and backflow from three hypodermic needles of 3 mm 34G (0.19 mm), 5 mm 32G (0.23 mm), and 8 mm 30G (0.30 mm) in length and thickness.
Methods
Ex vivo experiments were carried out on pigs, in neck tissue ...
Influence of hypodermic needle dimensions on subcutaneous injection delivery – a pig study of injection deposition evaluated by CT scanning, histology, and backflow is a post from: Skincare
Influence of hypodermic needle dimensions on subcutaneous injection delivery – a pig study of injection deposition evaluated by CT scanning, histology, and backflow via BuzzBlazer.com
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