Comparison of two encapsulated curcumin particular systems contained in different formulations with regard to in vitro skin penetration

Background

Curcumin is known for its anti-inflammatory, antioxidative, and anticarcinogenic properties. However, the strong lipophilic compound is not easily applicable, neither in water, nor directly in o/w formulations. So far, loading of nano or micro scaled carriers has enabled only an uptake up to 30% of curcumin.



Method

In the present article, curcumin was successfully encapsulated into two different safe and inexpensive polymers, ethyl cellulose and methyl cellulose blended ethyl cellulose with a loading capacity of ~ 46–48%. In addition, the in vitro skin penetration of the two curcumin encapsulated particular systems, which were ...

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