Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp – a randomized multicentre study

Abstract

Background:  Photodynamic therapy (PDT) is an attractive therapy for non-melanoma skin cancers and actinic keratoses (AKs). Daylight-mediated PDT is a simple and tolerable treatment procedure for PDT. Methyl aminolevulinate (MAL) -PDT is approved for the treatment of thin or non-hyperkeratotic actinic keratoses on the face and scalp. However, thick AK lesions are often treated as well when present in the field-cancerized treatment area.


Objectives:  The aim of the study was in a randomized multicentre study to evaluate efficacy of daylight-mediated PDT for different severity grades of AKs.


Methods:  145 patients with a ...

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