Background: Neoplastic T cells recruitment into the skin is a critical step in mycosis fungoides (MF) pathogenesis and the cutaneous T-cell attracting chemokine CTACK/CCL27 might be involved.
Objectives: Aim of our study was to investigate the clinical and prognostic significance of CTACK/CCL27 levels in patients with early stage MF.
Methods: Serum samples and skin biopsy specimens were collected from 15 patients at the time of the diagnosis, and after the end of treatment with PUVA/IFNα2b combination therapy. Serum samples were also collected from 20 healthy donors as controls. CTACK/CCL27 serum levels were ...
Serum and tissue CTACK/CCL27 chemokine levels in early mycosis fungoides and disease control by ifn-a and puva therapy. is a post from: Skincare
Serum and tissue CTACK/CCL27 chemokine levels in early mycosis fungoides and disease control by ifn-a and puva therapy. via BuzzBlazer.com
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