Long-Term Effectiveness and Safety of Small-Gel-Particle Hyaluronic Acid for Hand Rejuvenation

Background

Fillers to reverse the effects of fat atrophy can help restore the hands’ youthful appearance.



Objective

To evaluate the effectiveness and safety of small-gel-particle hyaluronic acid (SGP-HA) for hand rejuvenation through 1 year.



Materials and Methods

A prospective open-label study recruited adults with moderate to severe vascular, bony, and tendon prominence. After a topical anesthetic was applied, SGP-HA (maximum dose of 4.0 mL) was injected into the dorsum using a threading technique and distributed by massage.



Results

There were 16 patients with a mean ± SD age of 60.1 ± 5.3. Two weeks after treatment, vascular, tendon, and bony prominence and skin ...

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