Tuesday, September 13, 2011

Prophylactic antibiotics for the prevention of cellulitis (erysipelas) of the leg – results of the UK Dermatology Clinical Trials Network’s PATCH II trial

Abstract

Background:  Cellulitis (erysipelas) of the leg is a common, painful infection of the skin and underlying tissue. Repeat episodes are frequent, cause significant morbidity and result in high health service costs.


Objectives: To assess whether prophylactic antibiotics prescribed after an episode of cellulitis of the leg can prevent further episodes.


Methods:  Double-blind, RCT including patients recently treated for an episode of leg cellulitis. Recruitment took place in 20 hospitals. Randomisation was by computer generated code, and treatments allocated by post from a central pharmacy. Participants were enrolled for a maximum of 3 ...

Prophylactic antibiotics for the prevention of cellulitis (erysipelas) of the leg – results of the UK Dermatology Clinical Trials Network’s PATCH II trial is a post from: Skincare




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