Background: Pathophysiological mechanism of chronic urticaria is still poorly understood and its etiology is considered to have an autoreactive basis. Autologous serum and plasma skin tests compose the simplest ways for diagnosing autoreactive urticaria (autoantibodies, histamine releasing factor, and coagulation factors, especially “thrombin”) in a clinical setting. But there are still some questions about the specificity of these tests.
Objective: To evaluate the role of “autoreactivity” in pathogenesis of chronic urticaria by means of measuring plasma prothrombin fragments 1+2, which are used as markers of thrombin, and compare the autologous plasma ...
Evaluation of autologous plasma skin test in patients with chronic idiopathic urticaria is a post from: Skincare
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