Alterations in leucocyte subsets and histomorphology in normal appearing perilesional skin, early, and chronic hidradenitis suppurativa lesions

Summary

Background:  The current insight into the histopathological course of events during disease progression in hidradenitis suppurativa is fragmentary.


Objectives:  To identify histological alterations and leucocyte subsets in normal appearing perilesional, early, and chronic HS skins.


Methods:  In this observational study we examined skin samples from 8 perilesional, 6 early and 10 chronic prototypic HS lesions, as well as 4 healthy donors by using in situ immunostaining.


Results:  Perilesional skin showed mild psoriasiform hyperplasia and follicular plugging as well as a low-grade influx of tryptase+ mast cells, CD3+ T cells, CD138+ plasma cells and ...

Alterations in leucocyte subsets and histomorphology in normal appearing perilesional skin, early, and chronic hidradenitis suppurativa lesions is a post from: Skincare

Alterations in leucocyte subsets and histomorphology in normal appearing perilesional skin, early, and chronic hidradenitis suppurativa lesions via BuzzBlazer.com