Five Years of Experience Using a Dermal Substitute: Indications, Histologic Studies, and First Results Using a New Single-Layer Tool

Background

Dermal substitutes have been used in Europe since 1996 as a mean of reconstructing the dermal layer.



Objectives

To introduce the dermal substitute as a dual-stage reconstructing procedure using the dual-layer version and as a single-stage procedure, combining the single layer with a skin graft to achieve immediate closure. Our further objective was to evaluate the persistence of a commercial dermal substitute in the host’s dermal layer using serial histologic studies.



Materials and Methods

The dermal substitute used was a membrane made using a porous coprecipitate of type I bovine collagen and glycosaminoglycan organized ...

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