Comparison of the Efficacy of Intralesional Triamcinolone Acetonide and 5-Fluorouracil Tattooing for the Treatment of Keloids

Background

Hypertrophic scars and keloids may complicate wound healing secondary to trauma or surgery. A variety of treatment regimens have been used for treatment of keloids.



Objective

To compare 5-fluorouracil (5-FU) tattooing and intralesional steroid for treatment of keloids.



Methods

In this 44-week, double-blind, clinical trial, 40 patients were randomized into two study groups. Patients in group 1 were given intralesional triamcinolone acetonide (TAC), and patients in group 2 were treated with 5-FU tattooing; both groups received treatment every 4 weeks for 12 weeks. Lesions were assessed for erythema, pruritus, height, surface, and induration at baseline (initiation ...

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