Formation of Fibrosis After Nonablative and Ablative Fractional Laser Therapy

Background

Fractional laser therapy (FLT) has become a widely accepted modality for skin rejuvenation and has also been used in various other skin diseases.



Objective

To observe long-term histologic effects of nonablative and ablative FLT in the treatment of pigment disorders.



Methods

A randomized controlled observer-blinded study was performed in 18 patients with pigment disorders. Two similar test regions were randomized to receive FLT with intermittent topical bleaching or topical bleaching alone. Patients with ashy dermatosis (AD) and postinflammatory hyperpigmentation (PIH) were treated using nonablative 1,550-nm FLT (15 mJ/microbeam, 14–20% coverage), whereas patients with Becker’s nevus ...

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