Background: Vitiligo is an acquired depigmentation disorder resulting from selective destruction of melanocytes. The aryl hydrocarbon receptor (AHR) is vital to the regulation of melanogenesis and melanocyte proliferation and differentiation through modulating the expressions of the melanogenesis related genes. AHR mutations may negatively affect AHR proteins and its target genes. Therefore, we hypothesized that AHR polymorphisms might be involved in vitiligo via impacting the transcriptional activities of related genes as mentioned above.
Objectives: To evaluate the potential association between AHR polymorphisms and vitiligo susceptibility.
Methods: We performed a hospital-based, case–control study of ...
The association of functional polymorphisms in the aryl hydrocarbon receptor (AHR) gene with the risk of vitiligo in Han Chinese populations is a post from: Skincare
The association of functional polymorphisms in the aryl hydrocarbon receptor (AHR) gene with the risk of vitiligo in Han Chinese populations via BuzzBlazer.com
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