Granulomatous cheilitis (GC) is a poorly understood disease process belonging to the larger group of orofacial granulomatosis. The treatment of GC has proven exceedingly difficult. While a variety of treatments have been applied to GC, there has been no uniform or predictably successful model demonstrated in the literature. The poorly understood etiologic mechanisms underpinning GC has significantly hampered the development an effective approach to treatment. Those therapies that have shown promise principally consist of agents with anti-inflammatory activity such as corticosteroids and immunomodulatory medications. On a careful review of the ...
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