Protective effects of β-carotene and melanin against protoporphyrine IX-induced phototoxicity in the photo hen’s egg test

Summary

Purpose

The aim of our study was to evaluate the photoprotective potential of melanin and β-carotene against protoporphyrine IX-induced phototoxicity via photo hen’s egg test.



Methods

In three independent test groups, the yolk sac blood vessel system of hen’s eggs was exposed to protoporphyrine IX and irradiated with ultraviolet A (UVA). One of the test groups also received melanin to investigate its photoprotective capacity; another test group received β-carotene for the same purpose. Morphological changes and embryo lethality were recorded in these three test groups for a period of 24 h. The same parameters ...

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