Background
Quaternary ammonium compounds (Quats), such as benzalkonium chloride (BAC) and benzethonium chloride (BEC), are widely used as antibacterial active ingredients and preservatives in personal care products, disinfectants, and ophthalmic preparations. BAC is known to be a marginal irritant when patch tested at 0.15% aq. Data on BEC are limited.
Objective
To differentiate irritant from allergic patch test reactions to quaternary ammonium compounds.
Methods
Eight subjects who were considered likely to react based on history of rash after exposure to disinfectants or a history of prior positive patch test to BAC were recruited, as well ...
Visual and confocal microscopic interpretation of patch tests to benzethonium chloride and benzalkonium chloride is a post from: Skincare
Visual and confocal microscopic interpretation of patch tests to benzethonium chloride and benzalkonium chloride via BuzzBlazer.com
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