Wednesday, April 27, 2011

Seasonal variations in vitamin D levels in melanoma patients: a single-centre prospective pilot comparative study

Abstract

Background  More than 90% of vitamin D synthesis is dependent on UV exposure. Photosensitive disorders such as lupus erythematosus, protoporphyria and xeroderma require strict sun avoidance, and vitamin D deficiency has been demonstrated in these patients. Melanoma patients are also instructed to avoid sun exposure and may hence be expected to be vitamin D deficient.


Materials and methods  Winter and summer vitamin D levels were compared in a group of melanoma patients (n = 61) and age- and phototype-matched controls (n = 53) without photosensitive disorders.


Results  Oral supplementary vitamin D intake was reported in 32.7% ...

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