Background About 8–10% of the general population in Europe carry a null mutation in the filaggrin gene which is associated with early onset of atopic dermatitis as well as persistence into adulthood. No studies have investigated whether individuals with the homozygous filaggrin null genotype always develop dermatitis.
Objectives The aim of this study was to describe the natural history of individuals with no filaggrin expression.
Materials Three study populations were included: (i) a random sample of 3335 subjects aged 18–69 years from the general population in Copenhagen who underwent general health examination; (ii) ...
Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible is a post from: Skincare
Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible via BuzzBlazer.com
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