Background Many autoimmune diseases share common susceptibility loci suggesting similar underlying cellular mechanisms involved in disease expression.
Objectives The purpose of this investigation was to study 21 genetic variants in 14 genes that are confirmed autoimmune loci in a cohort of patients with early-onset psoriasis.
Methods Patients with early-onset psoriasis (n = 750) and controls (n = 3531) were genotyped using the Sequenom® MassArray™ iPLEX Gold platform.
Results We found strong evidence of association with two variants in the IL2/IL21 (rs6822844, genotypic P = 3.3 x 10−4; rs2069778 genotypic P = 7.86 x ...
A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21 is a post from: Skincare
A systematic investigation of confirmed autoimmune loci in early-onset psoriasis reveals an association with IL2/IL21 via BuzzBlazer.com
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