Wednesday, February 16, 2011

Immunofluorescence of the outer root sheath: an aid to diagnosis in pemphigus

Summary

Background.  The direct immunofluorescence (DIF) pattern of the outer root sheath (ORS) of the hair follicle in patients with pemphigus resembles that of perilesional skin. We performed DIF on anagen and telogen hair ORS from patients with pemphigus and compared the findings with those of perilesional skin.


Aim.  To assess the sensitivity of DIF in the ORS of anagen and telogen hair in patients with pemphigus with positive DIF results in perilesional skin.


Methods.  In total, 50 patients with active pemphigus and positive DIF findings in perilesional skin were selected for the ...

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