Background Various mediators of pruritus have been suggested to be responsible for the mechanism of pruritus in psoriasis.
Objectives The aim was to study the expression of members within the tachykinin family, substance P and neurokinin (NK) A and their receptors (R), NK-1 and NK-2 in psoriasis and to correlate their expression to the intensity of pruritus. A possible correlation with chronic stress and depression was also evaluated.
Methods Biopsies were obtained from 28 patients with chronic plaque psoriasis, the majority having pruritus. The samples were taken from the lesional and non-lesional ...
Expression of tachykinins and their receptors in plaque psoriasis with pruritus is a post from: Skincare
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