Objective: To examine the frequency of sensitization to preservatives, including time trends.
Methods: Retrospective analysis of data on patch testing preservatives contained in the standard series and special series collected by the IVDK 1996-2009.
Results: Some 120,000 and 80,000 patients were tested with the baseline and the preservative series, respectively. Sensitization frequencies of the standard series allergens all ranged above 1%: Methyldibromo glutaronitrile (MDBGN) 2.36 – 4.5%, methyl(chloro)isothiazolinone (MCI/MI) 2.22%, formaldehyde 1.54%, paraben mix 1.33% and Bronopol ™ 1.25%. Regarding the special preservative series, 1.54% reacted positive to methylisothiazolinone (MI), and less ...
Contact allergy to preservatives. Analysis of IVDK data 1996 – 2009 is a post from: Skincare
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