Efficacious and safe management of moderate-to-severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0.05% combined with ketoconazole shampoo 2%: a randomised, controlled study

Abstract

Background:  Topical antifungals and corticosteroids are mainstay of treatment for seborrhoeic dermatitis (SD). The short-contact clobetasol propionate 0.05% shampoo (CP) is an efficacious and safe once-daily treatment for scalp psoriasis.


Objective:  To evaluate the efficacy and safety of CP alone and combined with ketoconazole shampoo 2% (KC) in the treatment of moderate-to-severe scalp SD.


Methods:  This randomised and investigator-blinded study consisted of 3 phases, each lasting 4 weeks. During the treatment phase, subjects were randomised to receive KC twice weekly (K2), CP twice weekly (C2), CP twice weekly alternating with KC twice ...

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