Sunday, February 27, 2011

Photodynamic therapy reduces the histologic features of actinic damage and the expression of early oncogenic markers.

Abstract

Photodynamic therapy (PDT) has been shown to be effective to treat non-melanoma skin cancer (NMSC), especially, actinic keratosis (AK). Moreover there is sufficient evidence of its effectiveness to prevent the appearance of premalignant and malignant lesions in organ transplant recipients.


The aim of this study is to describe the molecular and genetic changes underlying this preventive effect. Therefore 22 patients were treated with using methyl-aminolevulinate and red light. Biopsies were performed before and six weeks after the treatment. Conventional histopathology and immunohistochemistry were carried out.


Not only was a reduction in the ...

Photodynamic therapy reduces the histologic features of actinic damage and the expression of early oncogenic markers. is a post from: Skincare




Photodynamic therapy reduces the histologic features of actinic damage and the expression of early oncogenic markers. via BuzzBlazer.com

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