Tuesday, May 3, 2011

Adverse effects of topical photodynamic therapy


Background/purpose: Topical photodynamic therapy (PDT) is increasingly used in dermatology, particularly for the treatment of superficial non-melanoma skin cancer and dysplasia. Treatment is generally considered to be well tolerated, although pain during PDT can be a limiting factor. This review explores the adverse effects of topical PDT.


Methods: A thorough search of the literature using Medline was undertaken and published data were evaluated and presented in conjunction with our own experience.


Results: Pain during PDT is the most commonly reported adverse effect and may prevent successful treatment delivery, although ...

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