BACKGROUND
Adipose tissue–derived stem cells (ASCs) are considered to be a reliable cell source for the generation of adipose tissue because they can be differentiated into adipocytes. Previous data have indicated that adipogenic differentiation of ASCs before transplantation can enhance the regeneration of adipose tissue.
OBJECTIVE
To evaluate the efficacy and safety of the use of autologous differentiated adipocytes for the treatment of depressed scars.
METHODS
Autologous differentiated adipocytes were produced using well-established techniques, including the harvesting of stromal vascular fraction cells from lipoaspirates, expansion of ASCs, and differentiation into adipocytes. This ...
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