Sunday, November 6, 2011

The influence of systemic therapy on the serum levels of IL-6 and IL-8 in pemphigus vulgaris

Abstract

Background  The place of cell-mediated immunity and cytokines in the immunopathogenesis of pemphigus vulgaris (PV) has not been fully established.


Objective  To assess the serum levels of pro-inflammatory cytokines, Interleukine-6 (IL-6) and Interleukine-8 (IL-8), in PV patients before and after therapy, to evaluate the influence of therapy on the serum cytokine levels.


Methods  Sixty-six newly diagnosed PV patients enrolled into the study. The serum levels of IL-8 and IL-6 were measured in 66 and 64 patients, respectively. According to the extent of skin and mucosal involvement, the patients were divided into two ...

The influence of systemic therapy on the serum levels of IL-6 and IL-8 in pemphigus vulgaris is a post from: Skincare




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