Thursday, November 10, 2011

Confocal laser microscopy, optical coherence tomography and transonychial water loss for in vivo investigation of nails

Abstract

Background:  Nail disorders can be diagnostically challenging to the dermatologist. Non-invasive methods might help to avoid nail biopsies. More knowledge of the typical features of healthy nails with these techniques is needed for comparison with nail diseases.


Objectives:  Objectives were to describe the typical morphology of healthy nails in optical coherence tomography (OCT) and confocal laser scanning microscopy (CLSM) and to examine the influence of exposure to water on OCT features, nail-thickness as well as on the transonychial water loss before and after a hand bath.


Material and Methods:  In the first ...

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