Background: Male-pattern baldness (androgenetic alopecia, AGA) is the most common form of hair loss among humans. Research has shown that it is caused by genetic factors. Numerous studies have unequivocally identified two major genetic risk loci for AGA: the X-chromosomal AR/EDA2R-locus; and the PAX1/FOXA2-locus on chromosome 20.
Objectives: To identify further candidate genes for AGA, and thus gain further insights into this phenotype.
Methods: A German sample of 581 severely affected cases and 617 controls was used to perform a genome-wide association study. The identified associated locus was further analyzed by fine-mapping, ...
Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness is a post from: Skincare
Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness via BuzzBlazer.com
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