Papulopustular rosacea (PPR) is a common facial skin disease, characterized by erythema, telangiectasia, papules and pustules. Its physiopathology is still being discussed, but recently several molecular features of its inflammatory process have been identified: an overproduction of Toll-Like receptors 2, of a serine protease, and of abnormal forms of cathelicidin.
The two factors which stimulate the Toll-like receptors to induce cathelicidin expression are skin infection and cutaneous barrier disruption: these two conditions are, at least theoretically, fulfilled by Demodex, which is present in high density in PPR and creates epithelial breaches ...
Papulopustular rosacea, skin immunity and Demodex: pityriasis folliculorum as a missing link is a post from: Skincare
Papulopustular rosacea, skin immunity and Demodex: pityriasis folliculorum as a missing link via BuzzBlazer.com
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