Thursday, March 24, 2011

New onset polyarthritis during successful treatment of hidradenitis suppurativa with infliximab

Abstract

Background:  Hidradenitis suppurativa (HS) can be associated with several forms of arthritis, usually considered as reactive arthritis. A new observation is that some HS patients develop arthritis after treatment with infliximab (anti-TNF-alpha).


Objectives:  A retrospective study was performed to establish the frequency and clinical presentation of new onset arthritis during infliximab treatment.


Methods:  Between 2005 and 2009, 27 individuals with severe HS were treated with infliximab and followed-up closely. Laboratory parameters and side-effects were recorded. The frequency of arthritis was compared to control groups consisting of 227 HS patients not treated with ...

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