Surgical scar remodelling after photodynamic therapy using Aminolevulinic-acid (ALA) or methyl-ester of ALA: a retrospective, blinded study of patients with field cancerization

SUMMARY

Background:  Photodynamic therapy (PDT) is a non-surgical alternative to conventional tumour excision for non-melanoma skin cancers (NMSC).


Objective:  We evaluated whether patients with field cancerization (multiple NMSC) treated with aminolevulinic acid (ALA) or methyl-ester of ALA (MAL) for that indication had PDT-induced changes in surgical scars in the treatment field.


Patients/Methods:  Six adult patients with multiple NMSC and a total of 21scars from previous excisions were studied in a retrospective blinded evaluation from clinical photographs of scar response to ALA/MAL-PDT. After a 3 hour application of topical 20% ALA or 16.8% MAL ...

Surgical scar remodelling after photodynamic therapy using Aminolevulinic-acid (ALA) or methyl-ester of ALA: a retrospective, blinded study of patients with field cancerization is a post from: Skincare

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