Abstract: A 10-month-old boy presented with a history of a generalized cutaneous bullous eruption since 3 months of age. Emesis, flush, pruritus, and fatigue had accompanied relapsing episodes of sometimes extensive blistering. Histopathology showed dense dermal infiltrates of mast cells on hematoxylin and eosin and corroborating immunohistochemical staining. Laboratory examination revealed a markedly high level of serum tryptase. Based on these results and after consecutive staging, the patient was diagnosed with diffuse cutaneous bullous mastocytosis (BM). Mutation analysis detected a deletion mutation (del419) in C-Kit by direct exon sequencing. This rare ...
Diffuse Cutaneous Mastocytosis Masquerading as Epidermolysis Bullosa is a post from: Skincare
Diffuse Cutaneous Mastocytosis Masquerading as Epidermolysis Bullosa via BuzzBlazer.com
No comments:
Post a Comment