Monday, August 29, 2011

Melanocytic naevi and basal cell carcinoma: is there an association?

Abstract

Background  Melanoma and basal cell carcinoma (BCC) affect similar body sites and share a complex relationship with sun exposure.


Objective  To establish the existence and magnitude of association between melanocytic naevi, the strongest predictors of melanoma, and BCC to give possible insights into shared pathways of solar ultraviolet tumourigenesis.


Methods  In a community-based longitudinal Australian study, detailed information was collected about sun sensitivity, and dermatologists assessed skin colour and counted naevi on the forearms (1986) and back (1992). The BCC frequency and sites were prospectively monitored until 2007. Multivariate logistic regression was ...

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