Nickel sensitization in orthodontically treated and non-treated female adolescents

Background. The importance of the nickel exposure from fixed orthodontic appliances is under continuous discussion.


Objectives. Our aim was to investigate nickel allergy and the risk of nickel sensitization among female adolescents during orthodontic treatment with fixed appliances as compared with non-treated female adolescents.


Subjects and methods. Female patients starting or with ongoing orthodontic treatment (n = 30) and young females without a history of orthodontic treatment (n = 140) were studied. Patch testing with 5% nickel sulfate was carried out twice on each participant with an approximately 1-year interval. The subjects ...

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