Is non-ablative 1550-nm fractional photothermolysis an effective modality to treat melasma? Results from a prospective controlled single-blinded trial in 51 patients

Abstract

Background  Melasma is a common benign pigmentary disease and can pose a substantial therapeutic challenge. Although the use of non-ablative fractional photothermolysis (NFP) has gained much popularity, there are still very few evidence-based data supporting NFP in the treatment of melasma.


Objective  To assess the efficacy and safety of NFP for the treatment of melasma in a controlled observer-blinded parallel-group study.


Patients and methods  Fifty-one patients [90.2% women, 9.8% men; mean age 40.3 ± 6.1 (control group) and 41.7 ± 11.4 (treatment group)] received a broad-spectrum sunscreen either alone (n = 25; 49.0%) or in combination with a ...

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